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American Restaurants in Downtown San Diego

Downtown San Diego lists 50 American restaurants across the Gaslamp Quarter, Little Italy, and the Harbor waterfront in 92101. The Crack Shack on India Street leads with 6,264 reviews, followed by Born and Raised (3,322 reviews) in the Gaslamp and Waterfront Bar & Grill (2,641 reviews) on the Embarcadero.

American in Downtown

All American

QUICK BITES CAFE / Best Sandwiches

5.0 (337)

1501 India St suite 105, San Diego, CA 92101

+1 619-902-0663

Vinarius Wine Bar & Restaurant

4.9 (607)

1445 India St, San Diego, CA 92101

+1 619-228-9930

Achilles Coffee Roasters @ Park 12

4.8 (293)

100 Park Plz Suite 175, San Diego, CA 92101

+1 619-292-8644

WetStone Winebar

4.8 (260)

1927 Fourth Ave, San Diego, CA 92101

+1 619-255-2856

BB's Deli

4.8 (220)

1321 Fifth Ave, San Diego, CA 92101

+1 619-238-4567

Postino Little Italy

4.8 (217)

2100 Kettner Blvd Suite 1800, San Diego, CA 92101

+1 619-241-4700

Black&Grey Atelier

4.9 (38)

1450 Market St A1, San Diego, CA 92101

+1 619-338-4000

American Comedy Co. San Diego

4.7 (3,387)

818 Sixth Ave, San Diego, CA 92101

+1 619-795-3858

The Shout! House

4.7 (2,686)

655 Fourth Ave, San Diego, CA 92101

+1 619-231-6700

The Balboa

4.7 (1,296)

1863 Fifth Ave, San Diego, CA 92101

+1 619-955-8525

Maestro Lounge

4.7 (674)

1352 Fifth Ave, San Diego, CA 92101

+1 619-325-1900

Swami's Café Downtown

4.7 (533)

611 B St, San Diego, CA 92101

+1 619-255-6731

Garibaldi

4.7 (413)

901 Bayfront Ct Suite 1, San Diego, CA 92101

+1 619-436-1081

Hidden Craft SD

4.7 (414)

600 W Broadway Suite 130, San Diego, CA 92101

+1 619-782-9113

Burgeon at The Arbor - Little Italy

4.7 (378)

1326 Kettner Blvd, San Diego, CA 92101

+1 619-432-1528

Cloud 9 Deli

4.7 (198)

1000 Island Ave Suite 61, San Diego, CA 92101

+1 619-432-1609

One WorldBeat Cafe

4.7 (114)

2100 Park Blvd, San Diego, CA 92101

+1 619-230-1190

Protector Brewery Hide Site

4.7 (71)

901 Bayfront Ct suite 102, San Diego, CA 92101

+1 619-994-8669

Hodad's Downtown

4.6 (4,395)

945 Broadway, San Diego, CA 92101

+1 619-234-6323

Azuki Sushi Lounge

4.6 (1,528)

2321 Fifth Ave, San Diego, CA 92101

+1 619-238-4760

CUCINA urbana

4.6 (1,995)

505 Laurel St, San Diego, CA 92101

+1 619-239-2222

Donut Bar & Bakery

4.6 (3,788)

401 W A St, San Diego, CA 92101

+1 619-255-6360

Island Prime

4.6 (2,519)

880 Harbor Island Dr, San Diego, CA 92101

+1 619-298-6802

The Lion's Share

4.6 (1,755)

629 Kettner Blvd, San Diego, CA 92101

+1 619-564-6924

The Taco Stand

4.6 (2,348)

645 B St, San Diego, CA 92101

+1 619-546-0570

Cowboy Star Restaurant and Butcher Shop

4.6 (1,007)

640 Tenth Ave, San Diego, CA 92101

+1 619-450-5880

Sweet Things

4.6 (287)

1 Park Blvd Suite #102, San Diego, CA 92101

+1 619-338-9555

Achilles Coffee Roasters @ The Rey

4.6 (251)

800 B St, San Diego, CA 92101

+1 619-259-0691

Grab & Go Subs

4.6 (255)

109 West C St # A, San Diego, CA 92101

+1 619-239-2739

Ali's Chicken & Waffles

4.6 (182)

1139 Sixth Ave, San Diego, CA 92101

+1 619-635-1269

Curbside Bites

5.0 (4)

1200 Columbia St, San Diego, CA 92101

+1 949-751-6192

MOE COFFEE LITTLE ITALY

4.6 (151)

2542 State St, San Diego, CA 92101

+1 858-405-7284

Grapes & Hops Deli

4.6 (92)

811 Market St, San Diego, CA 92101

+1 619-255-5383

El Cortez Gourmet Mart

4.5 (13)

702 Ash St, San Diego, CA 92101

+1 619-232-6730

F Street Café

4.5 (41)

530 F St, San Diego, CA 92101

+1 619-333-3098

Shibuya Nights

4.3 (8)

1953 India St Level 2, San Diego, CA 92101

+1 619-501-5505

Afternoon Tea at The Westgate Hotel

4.5 (102)

1055 Second Ave, San Diego, CA 92101

+1 619-238-1818

Bronze Bird

4.5 (194)

910 Broadway Cir, San Diego, CA 92101

+1 619-272-5840

Ciné Café

4.5 (243)

412 K St, San Diego, CA 92101

+1 619-595-1929

Ocho Mexican Food & Cafe

4.5 (225)

1870 Fourth Ave, San Diego, CA 92101

+1 619-310-5252

Cafe de L'Opera

4.5 (293)

910 J St, San Diego, CA 92101

+1 619-647-9676

Influx Cafe Little Italy

4.5 (344)

750 W Fir St #105, San Diego, CA 92101

+1 619-255-0735

The Grant Grill

4.5 (356)

326 Broadway, San Diego, CA 92101

+1 619-744-2077

Coffeentalk

4.5 (452)

1143 Sixth Ave, San Diego, CA 92101

+1 619-269-4977

TopSail

4.5 (410)

1360 N Harbor Dr, San Diego, CA 92101

+1 619-719-4961

Dobson's Bar & Restaurant

4.5 (490)

956 Broadway Cir, San Diego, CA 92101

+1 619-231-6771

Lani Coffee

4.5 (477)

101 Market St #100, San Diego, CA 92101

+1 619-299-5466

Señor Taquero

4.5 (490)

435 Broadway, San Diego, CA 92101

+1 619-550-5451

Stout Public House

4.5 (723)

1125 Sixth Ave, San Diego, CA 92101

+1 619-702-7933

Caffe Italia

4.5 (860)

1704 India St, San Diego, CA 92101

+1 619-234-6767

Neighborhood

4.5 (879)

777 G St, San Diego, CA 92101

+1 619-446-0002

Quartyard

4.5 (1,056)

1301 Market St #3, San Diego, CA 92101

+1 619-432-5303

Taste & Thirst

4.5 (910)

715 Fourth Ave, San Diego, CA 92101

+1 619-955-5995

The Corner Drafthouse

4.5 (784)

495 Laurel St, San Diego, CA 92101

+1 619-255-2631

Top of the Market - San Diego

4.5 (854)

750 N Harbor Dr, San Diego, CA 92101

+1 619-234-4867

Coin-Op Game Room

4.5 (1,545)

789 Sixth Ave, San Diego, CA 92101

+1 619-546-6441

Las Hadas Bar and Grill

4.5 (1,585)

558 Fourth Ave, San Diego, CA 92101

+1 619-232-1720

Melting Pot

4.5 (1,134)

901 Fifth Ave, San Diego, CA 92101

+1 619-234-5554

Puerto La Boca

4.5 (1,351)

2060 India St, San Diego, CA 92101

+1 619-234-4900

The Melt

4.5 (1,569)

635 Fifth Ave, San Diego, CA 92101

+1 619-356-7307

Zama San Diego

4.5 (1,355)

467 Fifth Ave, San Diego, CA 92101

+1 619-915-5789

Bencotto

4.5 (2,293)

750 W Fir St #103, San Diego, CA 92101

+1 619-450-4786

Born and Raised

4.5 (3,322)

1909 India St, San Diego, CA 92101

+1 619-202-4577

Buon Appetito Restaurant

4.5 (3,187)

1609 India St, San Diego, CA 92101

+1 619-238-9880

Cafe 222

4.5 (2,187)

222 Island Ave, San Diego, CA 92101

+1 619-236-9902

Craft & Commerce

4.5 (1,856)

675 W Beech St, San Diego, CA 92101

+1 619-269-2202

Kettner Exchange

4.5 (2,237)

2001 Kettner Blvd, San Diego, CA 92101

+1 619-255-2001

Landini's Pizzeria

4.5 (2,015)

1827 India St, San Diego, CA 92101

+1 619-238-3502

Mona Lisa Italian Foods

4.5 (4,937)

2061 India St, San Diego, CA 92101

+1 619-234-4893

Music Box

4.5 (2,097)

1337 India St, San Diego, CA 92101

+1 619-795-1337

Parfait Paris

4.5 (2,516)

555 G St, San Diego, CA 92101

+1 619-245-4457

Queenstown Public House

4.5 (2,934)

1557 Columbia St, San Diego, CA 92101

+1 619-546-0444

Richard Walker's Pancake House

4.5 (4,300)

520 Front St, San Diego, CA 92101

+1 323-726-2253

Shake Shack Little Italy

4.5 (2,026)

2008 India St, San Diego, CA 92101

+1 619-331-3958

Waterfront Bar & Grill

4.5 (2,641)

2044 Kettner Blvd, San Diego, CA 92101

+1 619-232-9656

The Crack Shack - Little Italy

4.5 (6,264)

2266 Kettner Blvd, San Diego, CA 92101

+1 877-230-1835

Silver Streak Cafe

4.3 (15)

Santa Fe Depot, San Diego, CA 92101

+1 619-531-0816

Fres.Co

4.4 (44)

L St, San Diego, CA 92101

+1 619-231-6664

Fred's Lunch Bag Deli

4.3 (27)

861 Sixth Ave UNIT 161, San Diego, CA 92101

+1 619-235-4434

Brisa Restaurant & Bar

4.4 (143)

2101 Kettner Blvd, San Diego, CA 92101

+1 619-303-0415

Miracle Potion Cafe & Tea Room

4.4 (171)

690 W B St, San Diego, CA 92101

+1 619-354-9730

Papanani's Deli

4.4 (187)

1450 Harbor Island Dr Dock B-46, San Diego, CA 92101

+1 619-383-1683

Pali Wine Co.

4.4 (200)

2130 India St, San Diego, CA 92101

+1 619-569-1300

Krisp Beverages + Natural Foods

4.4 (300)

969 Market St #101, San Diego, CA 92101

+1 619-310-6594

The Deck at Moonshine Flats

4.4 (597)

335 Sixth Ave, San Diego, CA 92101

+1 619-255-7625

Hazelwoods On the Bay

4.4 (661)

1355 N Harbor Dr, San Diego, CA 92101

+1 619-231-9866

Tivoli Bar and Grill

4.4 (840)

505 Sixth Ave, San Diego, CA 92101

+1 619-232-6754

Trailer Park After Dark

4.4 (872)

835 Fifth Ave Lower Level, San Diego, CA 92101

+1 619-236-1550

GARAGE Kitchen + Bar

4.4 (1,047)

655 Fourth Ave, San Diego, CA 92101

+1 619-231-6700

Burger Lounge

4.4 (1,326)

1608 India St, San Diego, CA 92101

+1 619-237-7878

Lofty Coffee Co.

4.4 (1,326)

444 W Cedar St, San Diego, CA 92101

+1 760-230-6747

Davanti Enoteca Little Italy

4.4 (2,173)

1655 India St, San Diego, CA 92101

+1 619-237-9606

Mimmo's

4.4 (1,776)

1743 India St, San Diego, CA 92101

+1 619-239-3710

Monello

4.4 (1,785)

750 W Fir St, San Diego, CA 92101

+1 619-501-0030

Barbusa

4.4 (2,547)

1917 India St, San Diego, CA 92101

+1 619-238-1917

Bub's at the Ballpark

4.4 (2,335)

715 J St, San Diego, CA 92101

+1 619-546-0815

Civico 1845

4.4 (3,043)

1845 India St, San Diego, CA 92101

+1 619-431-5990

Hob Nob Hill

4.4 (2,209)

2271 First Ave., San Diego, CA 92101

+1 619-239-8176

Breakfast Republic

4.4 (4,335)

707 G St, San Diego, CA 92101

+1 619-501-8280

Broken Yolk Cafe

4.4 (3,108)

355 Sixth Ave, San Diego, CA 92101

+1 619-338-9655

Carnitas' Snack Shack - Embarcadero

4.4 (3,410)

1004 N Harbor Dr, San Diego, CA 92101

+1 619-696-7675

Extraordinary Desserts

4.4 (4,719)

1430 Union St, San Diego, CA 92101

+1 619-294-7001

House of Blues San Diego

4.4 (3,662)

1055 Fifth Ave, San Diego, CA 92101

+1 619-299-2583

Fogo de Chão Brazilian Steakhouse

4.4 (7,076)

668 Sixth Ave, San Diego, CA 92101

+1 619-338-0500

Harbor & Sky Rooftop Bar and Lounge

4.3 (116)

900 Bayfront Ct, San Diego, CA 92101

+1 619-831-0224

Villains Brewing Company

4.3 (163)

903 Island Ave #15, San Diego, CA 92101

+1 619-232-9845

Mendocino Farms

4.3 (249)

180 Broadway Suite 102, San Diego, CA 92101

+1 619-398-3860

Appetite

4.2 (76)

401 W A St, San Diego, CA 92101

+1 619-236-8800

Gaslamp Lumpia Factory

4.3 (259)

423 F St, San Diego, CA 92101

+1 619-310-5522

Krisp Beverages + Natural Foods

4.3 (269)

1427 First Ave., San Diego, CA 92101

+1 619-232-8665

Starbucks

4.3 (279)

1450 Columbia St, San Diego, CA 92101

+1 619-889-0428

Tiger Café

4.3 (362)

345 Market St, San Diego, CA 92101

+1 619-866-2044

Canvas Café + Lounge

3.9 (27)

401 W Ash St, San Diego, CA 92101

+1 619-546-9600

The Rooftop

4.2 (100)

401 W Ash St, San Diego, CA 92101

+1 619-432-1441

skybound coffee + dessert lounge

4.3 (657)

181 W Market St, San Diego, CA 92101

+1 619-719-2010

Parakeet Cafe - Little Italy

4.3 (689)

1680 India St, San Diego, CA 92101

+1 619-255-1442

Petrini's San Diego

4.3 (818)

610 W Ash St #100, San Diego, CA 92101

+1 619-595-0322

Lionfish Modern Coastal Cuisine – San Diego

4.3 (863)

435 Fifth Ave, San Diego, CA 92101

+1 619-738-7200

Tender Greens

4.3 (1,129)

110 W Broadway, San Diego, CA 92101

+1 619-795-2353

Chocolate Cafe

4.3 (1,289)

509 Fifth Ave, San Diego, CA 92101

+1 619-238-9400

Cloak and Petal Little Italy

4.3 (1,328)

1953 India St, San Diego, CA 92101

+1 619-501-5505

Nolita Hall

4.3 (1,366)

2305 India St, San Diego, CA 92101

+1 619-255-8000

Sally's Waterfront Dining

4.3 (1,574)

1 Market Pl, San Diego, CA 92101

+1 619-358-6740

Harbor Breakfast

4.3 (1,974)

1502 India St, San Diego, CA 92101

+1 619-884-8948

Cafe Sevilla of San Diego

4.3 (3,614)

353 Fifth Ave, San Diego, CA 92101

+1 619-233-5979

Morning Glory

4.3 (3,497)

550 W Date St Suite #C, San Diego, CA 92101

+1 619-629-0302

Rustic Root

4.3 (2,854)

535 Fifth Ave, San Diego, CA 92101

+1 619-232-1747

Dunkin'

3.8 (26)

605 C St Suite A, San Diego, CA 92101

+1 619-310-5151

The Café at Alma San Diego

3.6 (22)

1047 Fifth Ave, San Diego, CA 92101

+1 619-515-3000

East Village Tavern+Bowl

4.2 (719)

930 Market St, San Diego, CA 92101

+1 619-677-2695

Topside Terrace Kitchen & Bar

4.1 (161)

421 W B St, San Diego, CA 92101

+1 619-398-3100

Vistal Bar + Restaurant

4.1 (224)

901 Bayfront Ct Suite 1, San Diego, CA 92101

+1 619-535-0485

Pressed Juicery

3.5 (31)

600 W Broadway #175, San Diego, CA 92101

+1 619-230-7233

Starbucks Coffee Company

4.1 (442)

Old Police Headquarters, 789 W Harbor Dr, San Diego, CA 92101

+1 619-234-0681

Coco Maya by Miss B's

4.1 (479)

1660 India St, San Diego, CA 92101

+1 619-257-2845

Brewery X

3.8 (61)

1380 Harbor Island Dr, San Diego, CA 92101

+1 619-692-2344

Dunkin'

4.1 (523)

225 Broadway #100, San Diego, CA 92101

+1 619-202-6739

Altitude Sky Lounge

4.1 (533)

Gaslamp Marriott Quarter, 660 K Street Atop, 660 K St, San Diego, CA 92101

+1 619-446-6089

Princess Pub & Grille

4.1 (1,288)

1665 India St, San Diego, CA 92101

+1 619-702-3021

Roy's Restaurant

4.1 (1,514)

333 W Harbor Dr, San Diego, CA 92101

+1 619-239-7697

The Cheesecake Factory

4.1 (4,453)

789 W Harbor Dr C-1, San Diego, CA 92101

+1 619-231-0036

Brickyard Coffee & Tea

4.0 (326)

675 W G St, San Diego, CA 92101

+1 619-228-9359

Starbucks Coffee Company

3.6 (59)

160 W Broadway, San Diego, CA 92101

+1 858-427-0800

Claim Jumper Steakhouse & Bar - San Diego, CA

4.0 (2,615)

1355 N Harbor Dr, San Diego, CA 92101

+1 619-531-7994

Subway

3.9 (328)

1080 Park Blvd Suite 1, San Diego, CA 92101

+1 619-544-0022

Gaslamp Burger

3.9 (334)

738 Fifth Ave, San Diego, CA 92101

+1 619-255-1839

Starbucks Coffee Company

3.9 (573)

600 W Broadway, San Diego, CA 92101

+1 619-233-0393

San Diego Burger Co.

3.9 (646)

879 W Harbor Dr Suite G, San Diego, CA 92101

+1 619-239-7901

Nekter Juice Bar

3.8 (239)

969 Market St Suite 150, San Diego, CA 92101

+1 619-955-5595

Subway

3.8 (387)

611 K St Suite A, San Diego, CA 92101

+1 619-525-0022

Phantom Lounge and Nightclub

3.3 (70)

1014 Fifth Ave #140, San Diego, CA 92101

+1 619-800-3303

Jack in the Box

3.8 (2,916)

1619 Pacific Hwy, San Diego, CA 92101

+1 619-232-7316

Omertà

3.1 (65)

777 Fifth Ave, San Diego, CA 92101

+1 619-356-4874

Burger King

3.6 (823)

1210 11th Ave, San Diego, CA 92101

+1 619-955-5966

Del Taco

3.6 (1,784)

1155 B St, San Diego, CA 92101

+1 619-239-8226

McDonald's

3.6 (4,109)

1280 Park Blvd, San Diego, CA 92101

+1 619-550-1823

Subway

3.4 (400)

1111 Sixth Ave Suite 100, San Diego, CA 92101

+1 619-702-7885

Jack in the Box

3.5 (2,557)

1110 C St, San Diego, CA 92101

+1 619-234-0785

50 American Restaurants in Downtown San Diego — Gaslamp Quarter, Little Italy & Waterfront

Top-Rated American Dining

The 50 American restaurant listings span brunch, steakhouses, gastropubs, and New American concepts across every Downtown district. The Crack Shack near Little Italy’s India Street corridor draws the largest review count at 6,264. Born and Raised on Fifth Avenue in the Gaslamp Quarter runs a white-tablecloth steakhouse program at 4.5 stars. Brunch pulls heavy search volume downtown — “San Diego brunch” hits 12,100 monthly queries — and Breakfast Republic (4,335 reviews), Broken Yolk Cafe (3,108 reviews), and Richard Walker’s Pancake House (4,300 reviews) anchor that category.

By District

The Gaslamp Quarter concentrates American dining along Fifth Avenue and Island Avenue — Rustic Root (2,854 reviews) sits in the heart of it. Little Italy and the Harborview waterfront add The Crack Shack, Carnitas’ Snack Shack (3,410 reviews), and The Taco Stand (2,348 reviews) along Kettner Boulevard and Harbor Drive. Island Prime (2,519 reviews) offers waterfront dining on Harbor Island with skyline views. The East Village ballpark area adds Kettner Exchange (2,237 reviews) and draws the Padres crowd from April through October. For American dining across the bay, see Coronado’s restaurant scene.

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