Hillcrest's longest-running women's transitional housing operation since 1942, Sister League of San Diego - Main Office runs its administrative center from 115 Redwood St in the 92103 ZIP code. Women transitioning through the program often require primary care coordination with nearby providers such as AHF Healthcare Center - San Diego. This location oversees weekly accountability sessions, goal-tracking assessments, and life-skill curricula including resume writing, interview preparation, and independent living instruction that structure each resident's path toward self-sufficiency. Donated furnishings and household essentials for the program's residences frequently come through community partners such as Father Joe's Villages Thrift Store & Donation Center - Hillcrest. The main office's most complex function involves coordinating multi-agency referrals through the San Diego Homeless Court Program to resolve outstanding misdemeanor warrants for incoming residents.