Nestled into the quieter north end of Pacific Beach at 5026 Cass St, 92109, Second Nature is a plant-forward American restaurant and wine bar that opened inside the former Turquoise Coffee space and quickly became one of the neighborhood's most talked-about all-day dining options. The kitchen builds a menu around fresh, sustainable ingredients with clearly marked vegan, vegetarian, and gluten-free dishes that go far beyond token salads, including vegan eggplant Parmesan with zucchini noodles, orange cauliflower, and an organic grass-fed beef burger for guests who prefer meat. Manager Rachael J. leads a team that reviewers praise for their knowledge of allergen-safe preparation, making Second Nature a reliable choice for diners managing celiac disease or dairy sensitivities. Breakfast staples like the Cali Brah Omelet and a Brazilian-approved acai bowl give way to a dinner service featuring teriyaki bowls, lettuce cup appetizers, and short rib plates, all complemented by a curated wine list, local craft beers, and specialty teas. Wine enthusiasts walking the Cass Street corridor can also stop into Enoteca Adriano for Italian wines and small plates a few doors down. The eco-chic interior carries a cozy, quiet atmosphere that sets it apart from the louder bar scene closer to the boardwalk, while the spacious patio welcomes dogs and even offers a dedicated pup-friendly menu. Second Nature holds a 4.4-star Google rating across more than 620 reviews and opens daily at 8 a.m., with weekend brunch drawing steady crowds by mid-morning. Diners looking for a different flavor profile on the north end of PB can head to PB Sushi on Garnet for hand-rolled sushi and Japanese beer.