Motel 6 San Diego, CA - Downtown in downtown San Diego holds 105 rooms at 1546 Second Avenue, a G6 Hospitality property positioned off the I-5 Sixth Avenue exit for direct freeway access to the city’s central corridor. Rooms feature modernized interiors with granite bathroom countertops, wood-effect flooring, and flat-screen cable TVs — a recent renovation standard shared across the Second Avenue lodging strip that also includes Baymont by Wyndham San Diego Downtown. The property accepts pets with a maximum of two per room, offers coin-operated laundry on-site, and serves complimentary lobby coffee each morning. Waterfront Park and the B Street Cruise Ship Terminal sit within a mile, and the San Diego Trolley’s Civic Center station connects the motel to Old Town, Mission Valley, and the U.S.-Mexico border crossing at San Ysidro. That central grid position keeps the Embarcadero’s waterfront dining — including New American kitchens like Kettner Exchange on Kettner Boulevard — within a 15-minute walk west. An elevator-equipped multi-story layout with ADA-accessible rooms featuring roll-in showers and grab bars handles the property’s most specialized accommodation configurations.