Point Loma's 11 pharmacies in 92106 and 92110 line the Rosecrans corridor and Midway District, with Ralphs Pharmacy combining prescriptions and grocery shopping on Rosecrans—serving residents, hotel guests near Shelter Island, and military families stationed on the south peninsula.
3245 Sports Arena Blvd, San Diego, CA 92110
+1 619-471-0030
Verified3345 Sports Arena Blvd, San Diego, CA 92110
+1 619-222-5818
Verified3327 Rosecrans St, San Diego, CA 92110
+1 619-225-9691
Verified3245 Sports Arena Blvd, San Diego, CA 92110
+1 619-471-0030
Verified2495 Truxtun Rd Bldg 28, San Diego, CA 92106
+1 619-758-9004
Verified3950 W Point Loma Blvd, San Diego, CA 92110
+1 619-523-1440
Verified3645 Midway Dr, San Diego, CA 92110
+1 619-222-9736
Verified3005 Midway Dr, San Diego, CA 92110
+1 619-221-0834
Verified3950 W Point Loma Blvd, San Diego, CA 92110
+1 619-523-1440
Verified3005 Midway Dr, San Diego, CA 92110
+1 619-221-0834
Verified3851 Rosecrans St, San Diego, CA 92110
+1 619-692-5740
VerifiedPoint Loma lists 11 pharmacies across the 92106 and 92110 ZIP codes, including chain drugstores on Rosecrans Street, grocery-store pharmacies, and independent dispensaries. Ralphs Pharmacy on Rosecrans combines prescription services with the convenience of a full grocery store, making it a practical stop for residents who fill prescriptions during a regular shopping trip.
Chain pharmacies operate additional locations along the Rosecrans and Sports Arena corridors, providing the peninsula with consistent hours and insurance-network coverage. Point Loma's pharmacy roster is geographically concentrated along the main commercial arteries, so residents in the southern peninsula neighborhoods near Sunset Cliffs and Cabrillo face a slightly longer drive to fill prescriptions than those near the Midway District.
Shelter Island sits at the western edge of Point Loma, and the closest pharmacies are located east along Rosecrans Street. Ralphs Pharmacy and the chain drugstores on Rosecrans are the nearest options for hotel guests, marina visitors, and residents near the Shelter Island waterfront.
Patients staying at Shelter Island hotels who need a prescription filled in a hurry should ask the front desk for the nearest location by current hours, since pharmacy closures on weekends or evenings can shift the closest open option. Shelter Island Medical Group can write prescriptions on site but does not dispense medications, so a pharmacy trip is still required after a doctor visit.
Point Loma does not currently have a 24-hour pharmacy on the peninsula. The chain drugstores along Rosecrans and in the Midway District operate on standard retail hours, typically closing between 9 and 10 p.m. on weekdays and earlier on weekends.
Residents who need a prescription filled late at night or in the early morning hours should check for 24-hour locations in Hillcrest or downtown San Diego, both of which are accessible from Point Loma via Pacific Highway or Interstate 8. Calling ahead to confirm current hours before driving is the safest approach, as pharmacy hours can shift seasonally or due to staffing.
Some of Point Loma's pharmacies offer prescription delivery, either through their own delivery service or via third-party apps. Chain pharmacies have expanded delivery and mail-order options in recent years, and patients enrolled in auto-refill programs can often have medications shipped directly to their homes in the 92106 and 92110 ZIP codes.
Delivery is especially relevant for seniors and homebound patients on the peninsula who cannot easily drive to Rosecrans or the Midway District. Patients should ask their pharmacy about delivery fees, turnaround times, and whether controlled substances can be included in deliveries, as regulations vary by medication type.
Compounding pharmacies prepare custom medications—adjusted dosages, allergen-free formulations, flavored liquid versions for children—that are not available in standard commercial form. Point Loma's pharmacy roster does not currently include a dedicated compounding pharmacy on the peninsula.
Residents who need compounded prescriptions typically use compounding pharmacies in Hillcrest, downtown San Diego, or the Mission Valley area. Prescriptions for compounded medications require a specific order from the prescribing physician, and turnaround times are usually longer than standard fills since each prescription is prepared individually. Asking your primary care provider for a compounding pharmacy referral is the fastest route.
Prescription costs without insurance vary dramatically by medication, ranging from under $10 for common generics to hundreds of dollars for brand-name drugs. GoodRx and similar discount-card programs can reduce cash prices at Point Loma pharmacies by 30 to 80 percent on many generics, and pharmacists will typically run a discount card alongside any existing coverage to find the lower price.
Patients who take multiple medications without insurance should ask their prescribing doctor about therapeutic alternatives—a less expensive drug in the same class can sometimes deliver the same benefit at a fraction of the cost. Ralphs Pharmacy and the chain drugstores in the Midway District all accept major discount-card programs at the register.
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