Enterprise Rent-A-Car's Pacific Beach branch at 2780 Garnet Ave, San Diego, CA 92109 operates inside the Handlery Hotel near the intersection of Garnet Avenue and Mission Bay Drive, sharing the Garnet corridor with Meineke Car Care Center on nearby Damon Avenue, which sometimes coordinates rental referrals for customers whose repair jobs run longer than expected. Enterprise Holdings, founded by Jack Taylor in 1957 in St. Louis, Missouri, has grown into the world's largest rental car company, and this Garnet Avenue location leverages the brand's signature complimentary pickup service — staff will drive to your home, office, or repair shop to collect you and bring you back to the branch. The location stocks a rotating fleet of economy cars, sedans, SUVs, and minivans, and offers active military discounts on most rentals with valid ID. Renters aged 21 to 24 can still book but should expect a young driver surcharge of $10 to $25 per day. The branch is open Monday through Friday 8 a.m. to 6 p.m. and Saturday 9 a.m. to noon, closed Sundays. Note that no overnight parking is available at this location and street parking nearby is limited. The branch has a close working relationship with neighboring auto repair shops — Yelp reviewers specifically mention Enterprise shuttling customers to and from the Caliber Collision center on Mission Bay Drive, a common arrangement for drivers who need a rental while their car undergoes body work. Visitors renting for a weekend beach trip can reach Crystal Pier, Belmont Park, and SeaWorld within a 10- to 15-minute drive from this centrally located branch.