Quixote at 2223 El Cajon Blvd operates inside the Lafayette Hotel, a property originally opened in 1946 and now listed on the National Register of Historic Places, where a decommissioned Mexican Catholic church was reconstructed to form the dining room and bar in North Park's 92104 ZIP code. The Oaxacan-accented menu shares a cocktail-driven customer base with Botanica Art & Cocktail Bar, both drawing mezcal and spirits enthusiasts to the neighborhood. A salvaged pulpit serves as the bar, baroque pews double as seating, and stained-glass windows frame a menu built around moles, heirloom masa, and shareable antojitos featuring duck, seafood, and regional Oaxacan ingredients. Upscale diners exploring North Park's dining corridor pair the restaurant with Siamo Napoli Restaurant on 30th Street for multi-stop evenings. The kitchen's most demanding service comes from private-event buyouts that combine coursed tasting menus with custom mezcal pairings inside the hotel's historic event spaces.