Sandwich shop at 8657 Villa La Jolla Dr, Suite 101 in La Jolla, 92037, home to over 800 creative combinations that have made Ike's a cult phenomenon since founder Ike Shehadeh opened the original San Francisco Castro location on Halloween 2007. The La Jolla location — the 97th in the chain — brings the full lineup: freshly sliced meats, real cheeses, and five plant-based protein options across sandwiches built with Ike's signature dirty sauce combinations you won't find anywhere else. Vegetarian, vegan, gluten-free, and halal options make sure nobody gets left out. Order in-store, on the Ike's app, or online — catering trays are available for groups. Open daily 10am–10pm. If you haven't tried Ike's yet, this is the place to start your quest through the menu.