Sandwich shop at 8657 Villa La Jolla Dr, Suite 101 in La Jolla, 92037, home to over 800 creative combinations that have made Ike's a cult phenomenon since founder Ike Shehadeh opened the original San Francisco Castro location on Halloween 2007. The La Jolla location — the 97th in the chain — shares the Village Square with Mendocino Farms, the two giving the plaza two of its strongest counter-service lunch options. Freshly sliced meats, real cheeses, and five plant-based protein options across sandwiches built with Ike's signature dirty sauce combinations you won't find anywhere else. Vegetarian, vegan, gluten-free, and halal options make sure nobody gets left out. Order in-store, on the Ike's app, or online — catering trays are available for groups. Open daily 10am–10pm, and Village diners who want their sub on house-baked Dutch crunch head to Rubicon Deli on La Jolla Village Drive.