Wayne O. Kurisu, MD operates an internal medicine practice on the third floor of Sharp Rees-Stealy Downtown at 300 Fir Street in downtown San Diego's Bankers Hill. The practice manages complex multi-system conditions—including depression, arthritis, diabetes, and geriatric decline—with behavioral health referrals to psychiatrists such as SILVERLINING Psychiatry Medical Group for medication co-management. Board-certified in internal medicine with a 1996 degree from the University of California San Francisco School of Medicine and residency at UC San Diego Medical Center, the practitioner has maintained active clinical practice since 1999. Published breast-cancer research in journals including Cancer Research and Breast Cancer Research and Treatment adds translational-science depth to a primary care practice focused on preventive medicine, smoking cessation, weight management, and tuberculosis screening. Geriatric patients managing age-related functional decline receive coordinated care plans that account for the assisted-living resources in the Bankers Hill corridor, including HarborView Senior Assisted Living on Third Avenue. The practice specializes in polypharmacy reconciliation and multi-morbidity management for elderly patients presenting with concurrent cardiovascular, metabolic, and musculoskeletal conditions requiring integrated treatment protocols.