Akeso Occupational Health San Diego on Fifth Avenue in downtown San Diego provides workplace injury treatment, compliance testing, and employer medical programs from a clinic opened in 2023. DOT physicals, pre-placement health screenings, and post-accident drug and alcohol testing are administered on site alongside workers' compensation prescription coordination with University Compounding Pharmacy in Bankers Hill for employees requiring custom-compounded injury medications. Akeso operates as California's largest independent occupational health provider, serving federal, state, county, and Fortune 500 employers across a statewide network of more than 20 clinics, with this Fifth Avenue suite opening as the downtown San Diego anchor. Audiometric testing, pulmonary function testing, and HazMat medical surveillance meet OSHA-mandated exposure monitoring requirements for construction crews, port workers, and laboratory technicians in the downtown corridor. Workers' compensation case management coordinates injured-employee care between the clinic's physicians, employer HR departments, and insurance adjusters to minimize lost workdays, with after-hours new-injury triage available at Sharp Rees-Stealy Downtown Urgent Care. Highest-tier compliance services include Federal Motor Carrier Safety Administration medical examiner physicals, OSHA-mandated respirator fit testing, and Cal/OSHA aerosol transmissible disease exposure protocols for healthcare and first-responder employers.