San Diego Zoo Wildlife Alliance in downtown San Diego's Balboa Park is a 501(c)(3) international conservation organization founded in 1916 by physician Harry Wegeforth, operating the San Diego Zoo and the San Diego Zoo Safari Park from its headquarters at 2920 Zoo Drive. The Alliance manages over 15,000 animals representing more than 750 species across both parks and maintains the Frozen Zoo, the world's largest cryogenic wildlife biobank with cell lines from over 11,500 individuals of more than 1,300 species—a genetic archive that complements the regional biodiversity research at the San Diego Natural History Museum elsewhere in the park. Conservation field programs operate across eight global hubs, and the Alliance has reintroduced more than 44 endangered species to native habitats, including California condors, Przewalski's horses, and southern white rhinoceros. The 100-acre Zoo houses over 12,000 animals and 700,000 plants representing 3,100 botanical species, functioning as an accredited botanical garden within the same Balboa Park science corridor anchored by the Fleet Science Center. The Alliance's most technically complex undertaking is its wildlife cloning and assisted reproduction program, which produced parthenogenetic California condor hatchlings—chicks born from unfertilized eggs—advancing genetic rescue techniques for critically endangered species worldwide.