Hotel Republic San Diego, Autograph Collection in downtown San Diego occupies 421 West B Street as a 258-room Marriott Autograph Collection property in the Columbia district between Little Italy and the Gaslamp Quarter. The Topside Terrace Kitchen & Bar serves rooftop cocktails and California-coastal plates with panoramic downtown views, while a ground-floor restaurant handles the dining program from breakfast through dinner alongside waterfront seafood houses like Sally's Waterfront Dining on the Embarcadero. Guest rooms feature flat-screen HDTVs, mini-refrigerators, and oversize work desks with natural-light window seats, and all categories accept pets up to 50 pounds. Over 16,000 square feet of indoor and outdoor meeting space spans 12 configurable venues — including a 2,600-square-foot ballroom and a rooftop terrace — supporting corporate events and weddings within walking distance of Music Box on Eleventh Avenue. The Presidential Suite and Veranda Club lounge anchor the property's premium tier for Marriott Bonvoy Platinum and Ambassador Elite members.