This Enterprise Rent-A-Car in downtown San Diego, set on Kettner Boulevard five minutes from SAN, serves Little Italy, Harbor Island, Mission Hills, Hillcrest, and Old Town without the airport concession surcharge. The lot handles cruise-port pickups directly — passengers disembarking at the B Street Pier call the branch for transport — a marine-transit link that off-airport competitors on nearby India Street, including Economy Rent A Car, do not offer. Enterprise Holdings designates this branch women-owned and extends active-duty military surcharge waivers on all vehicle classes from economy sedans through 15-passenger vans. Fleet vehicles returning from weekly rentals clear a rapid-turnaround inspection cycle, and the 92101 zip's concentration of mobile detailing operators — including Above The Next Detail — gives this branch same-day reconditioning access that suburban locations lack. The highest-demand bookings cover multi-week convertible rentals for snowbird visitors and month-long cargo-van packages for Little Italy restaurant buildouts on India Street.