Directed by a board-certified dermatologist and Fellow of the American Academy of Dermatology, Refine Acne Clinics on Kettner Boulevard in downtown San Diego's Little Italy corridor provides dermatologist-supervised acne treatment plans combining prescribed medications with in-office protocols. Customized treatment regimens may include compounded topical formulations — prescription-strength retinoids, antibiotics, and azelaic-acid preparations — that require the specialized dispensing capabilities of a compounding pharmacy, a service provided by University Compounding Pharmacy in Bankers Hill, where pharmacists adjust concentration, vehicle, and active-ingredient combinations per the dermatologist's specifications. The clinic initiates care through an online consultation platform where the supervising dermatologist reviews submitted photos and medical history to design a protocol before the patient's first in-office visit, eliminating the four-month-plus wait time typical of traditional dermatology scheduling. In-office treatments address active acne, post-inflammatory hyperpigmentation, and early scarring through a combination of chemical peels, extractions, and LED phototherapy calibrated to the online consultation's diagnostic findings. Refine's multi-month treatment courses require patients to manage appearance while active lesions clear, and the clinic's product guidance extends to recommending non-comedogenic coverage options — a cosmetic dimension that parallels the corrective-makeup services at Triplow Beauty for patients needing event-ready coverage during active treatment phases. The facility specializes in medical-grade salicylic and glycolic acid peels at concentrations exceeding 20% for controlled desquamation of comedonal and inflammatory acne lesions, combined with prescription-strength tretinoin and spironolactone protocols for hormonal acne in adult patients.