Brian Matthew Kleker, MD is a board-certified dermatologist affiliated with Kaiser Permanente Zion Medical Center at 4647 Zion Avenue in Allied Gardens, San Diego 92120. He earned his medical degree from the University of Colorado School of Medicine in 2008 and completed a combined internal medicine and dermatology residency at the University of Wisconsin Hospitals and Clinics between 2008 and 2013, giving him dual-specialty training that informs his approach to systemic skin diseases with internal medicine overlap. California medical license A125914 covers his practice within the Southern California Permanente Medical Group. Oral mucosal lesions presenting in both skin and oral tissue — conditions such as lichen planus and pemphigus — occasionally generate cross-referrals with dental providers including Alvarado Dental Group in Grantville, where oral pathology intersects with dermatologic diagnosis. Dr. Kleker's clinical work includes medical dermatology for acne, psoriasis, eczema, and actinic keratosis, alongside procedural dermatology involving skin biopsies, excisions, cryosurgery, and Mohs micrographic surgery for skin cancer. His published research — including work on Mohs surgery for localized cutaneous alternariosis and a peer-reviewed study on eosinophilic fasciitis in The Permanente Journal — reflects a practice grounded in evidence-based dermatologic care. The Kaiser Zion campus in Allied Gardens sits near the Waring Road commercial district, approximately a mile and a half from SDSU, serving Kaiser members across the 92120 ZIP and extending into the broader East County referral network. Dr. Kleker also maintains a practice location at Kaiser's La Mesa Medical Offices on Parkway Drive, splitting his caseload between two East County sites. Patients managing chronic skin disease with documented behavioral health impact coordinate care through providers including LifeStance Therapists & Psychiatrists San Diego in Grantville for the anxiety and depression component that dermatologic research links to persistent psoriasis and eczema. His dual internal medicine and dermatology background positions him to manage autoimmune skin conditions — lupus, dermatomyositis, scleroderma — that require coordination with rheumatology and other internal medicine subspecialties.