One Heart Worldwide is a San Diego–based international health nonprofit that maintains its U.S. administrative office in San Carlos at 8141 El Extenso Court, coordinating maternal and neonatal health programs for underserved rural communities in Nepal. Founded in 2004 as a 501(c)(3) under EIN 30-1032421, the organization built its operational model on more than a decade of prior field work in the Tibetan Autonomous Region before shifting its primary focus to Nepal's most remote districts. International health organizations headquartered in San Diego share a regional infrastructure with groups such as Foundation for the Children of the Californias, which addresses pediatric healthcare gaps along the U.S.-Mexico border from its own Grantville base. OHW's Network of Safety model trains skilled birth attendants, equips birthing centers, and mobilizes Female Community Health Volunteers across a six-year implementation cycle designed to hand off a fully functional maternal and neonatal health system to local government ownership. Since 2010, the program has reached nearly one million women and newborns across Nepal, with a stated goal of improving access to quality care for 250,000 pregnancies annually—one third of all annual pregnancies in the country—by 2030. A USAID American Schools and Hospitals Abroad grant funds the creation of seven MNH Centers of Excellence across Nepal, a joint project between the United States government, the Government of Nepal, and One Heart Worldwide targeting Sustainable Development Goal benchmarks for maternal mortality reduction. The San Diego office supports a team of roughly 73 employees, the majority of whom are Nepali health workers operating in-country while a small technical team in San Carlos manages grant compliance, donor relations, and program evaluation. El Extenso Court sits in the San Carlos residential grid near Lake Murray, and the San Carlos Branch Library on Lake Murray Boulevard serves as a neighborhood resource point in the same 92119 ZIP where OHW's stateside team manages the data systems behind a $2-million-plus annual budget. The six-year Network of Safety cycle results in well-trained birth attendants providing quality care at fully equipped birthing centers, a cadre of empowered community health volunteers, and local fiscal ownership that sustains delivery systems after OHW's direct involvement concludes.