Ayres Hotel San Diego South in Chula Vista's Eastlake corridor is a 135-room, four-story California mission-style property built in 2019 on Millenia Avenue off Highway 125 near Otay Ranch Town Center. The on-site Winners Circle restaurant and poolside sports bar anchor an evening dining program distinct from the taproom format at nearby Novo Brazil Brewing - Otay Ranch. Ayres Hotels, a Southern California chain, equips each roughly 490-square-foot room with laptop-compatible workspaces, flat-screen TVs with satellite, in-room safes, and coffee-and-tea service. The property's 1,600-plus square feet of meeting space includes the 1,100-square-foot Millenia Room configurable for 75 attendees in theater layout and a fourth-floor boardroom seating 15, supplementing weekend family itineraries built around Salt Creek Recreational Center in the Otay Ranch residential zone. The heated outdoor pool, hot tub, full-service gym, EV-charging station, and pet-welcoming policy round out a facility spec that positions the Millenia Avenue location three miles from the Chula Vista Elite Athlete Training Center and five miles from Sesame Place San Diego.