Castillejos Eye Institute on Chula Vista's F Street has been anchored by Maria E. Castillejos, MD since 1983, making it one of the longest-operating ophthalmology practices in the South Bay. Board-certified by both the American Board of Ophthalmology and the Consejo Mexicano de Oftalmologia, she graduated magna cum laude from Universidad Nacional Autonoma de Mexico before completing a retina and vitreous fellowship at Harvard's Massachusetts Eye and Ear Infirmary under Dr. Charles Schepens—a surgical training lineage that informs the institute's diabetic retinopathy referral pipeline shared with practices such as Cardiovascular Institute of San Diego for patients with concurrent cardiovascular and retinal vascular disease. Scripps-affiliated and fluent in Spanish, Portuguese, Italian, and Tagalog, she treats general ophthalmology, glaucoma, cataracts, and oculoplastic conditions from the 342 F Street campus near Third Avenue. Acute ocular trauma and sudden-onset vision loss cases arriving outside standard scheduling may first present at Marque Urgent Care before transfer to the institute for definitive vitreoretinal evaluation. The surgical suite supports 25-gauge transconjunctival pars plana vitrectomy with wide-angle viewing systems and endo-laser photocoagulation for proliferative diabetic retinopathy and rhegmatogenous retinal detachment repair.